Scientific Advisory Board
Charles L. Wiseman, MD, FACP
Founder and Principal Research Advisor
Dr. Wiseman brings more than 40 years of academic and clinical experience to BriaCell Therapeutics Corp. As Co-Founder of BriaCell, he is the inventor for most of the Company’s intellectual property and actively participates in its ongoing technology development. During his career, Dr. Wiseman has managed numerous clinical development teams and programs, with a focus in oncology, tumor immunology, vaccine development, and genetics. | Show More
He was previously the principal investigator for immunotherapy treatment protocols at the St. Vincent Cancer Treatment Center and the Los Angeles Oncologic Institute.As the former Director of the Breast Cancer Basic Research Laboratory at the University of Texas MD Anderson Hospital in the 1970s, Dr. Wiseman was one of the pioneers of the field of cancer vaccine therapeutics.Dr. Wiseman has served as Clinical Professor of Medicine at the Division of Medical Oncology, Keck-USC School of Medicine, and previously was Acting Chief of the Division of Oncology/Hematology at White Memorial Medical Center. Dr. Wiseman has been cited in US News Top Doctors yearly since 2002.Dr. Wiseman received his a B.S. at UCLA as Outstanding Student of Chemistry, and received his MD degree there also, serving as President of the Student American Medical Association.Dr. Wiseman has written in over 100 peer-reviewed publications and medical textbook chapters. | show less
Doug Faller, MD, PhD
Dr. Faller is a Professor of Medicine, Pediatrics, Biochemistry, Microbiology, Pathology and Laboratory Medicine; former Director of the Cancer Center; and former Vice-Chairman, Division of Medicine, of Boston University School of Medicine. He is a hematologist/oncologist, author of hundreds of scientific papers and recipient of numerous grants. He is an acknowledged expert in basic molecular and cellular biology of virus- and oncogene-transformed cells and tumors. | Show More
He leads a translational research program which develops molecular cancer therapeutics derived from his basic research, and tests them in clinical trials. He has been the scientific founder of several biotech start-ups including HemaQuest Pharmaceuticals, Phoenicia Biosciences and Viracta Therapeutics. | show less
Cara L. Haymaker, PhD
Dr. Cara Haymaker is an assistant professor at Department of Translational Molecular Pathology, Division of Pathology/Lab Medicine at The University of Texas MD Anderson Cancer Center. She has been appointed as Director, CCSG Oncology Research and Immunomonitoring Core, Department of Translational Molecular Pathology, Division of Pathology and Lab Medicine since 2018, and as Faculty Member, Translational Molecular Pathology Immunoprofiling Laboratory (TMP-IL) since 2016 at MD Anderson. | Show More
Dr. Haymaker’s research has focused on Tumor-infiltrating Lymphocytes and their Immunologic Characteristics in solid tumors. Dr. Haymaker earned a PhD in immunology from University of Missouri, Columbia, MO, and has completed her Postdoctoral Fellowship at MD Anderson. She has authored 45 peer-reviewed original research articles. | show less
Alexander Kharazi, MD, PhD
Dr. Kharazi co-invented Bria-IMT™, BriaCell’s lead clinical candidate, in collaboration with Dr. Charles L. Wiseman, BriaCell’s Founder and Principal Research Advisor. Dr. Kharazi currently serves as Chief Technology Officer at Stemedica Cell Technologies, Inc. His experience includes roles as Chief Scientist of the Immunotherapy laboratory at St. Vincent Medical Center in Los Angeles (1998-2006) and Chief Pathologist of a large good laboratory practice (GLP) animal study at the University of California, Los Angeles (UCLA) (1991-1998) reporting results to the U.S. Congress. | Show MoreAdditionally, he has worked as a Research Fellow in the department of Pathology at the Tokyo Metropolitan Institute of Gerontology in Japan from 1989 to 1991. Dr. Kharazi earned his Ph.D. in immunology and his medical degree in internal medicine and pathology in Kiev, Ukraine. He is a named inventor on eight U.S. patents and several foreign patents. He is the author of numerous U.S. and international publications and has been an invited speaker/chairman/panelist on several scientific meetings. | show less
Thomas Kieber-Emmons, PhD
Dr. Kieber-Emmons is known for his work on molecular and structural immunology, developing peptide mimetics of carbohydrate antigens as vaccines in both the cancer and pathogen areas, an acknowledged pioneer in this field. Dr. Kieber-Emmons has both translational and clinical trial experience. Dr. Kieber-Emmons has brought the first carbohydrate mimetic peptide through preclinical development to Phase II Clinical Trials in Breast Cancer and in other cancer indications. | Show More
Dr. Kieber-Emmons was recruited from the University of Pennsylvania in 2002 to the University of Arkansas for Medical Sciences where he holds the Jossetta Wilkins Chair in Breast Cancer Research, and is a Director at the Winthrop P. Rockefeller Cancer Institute. | show less
Brian Metcalf, PhD
Dr. Metcalf recently retired as CSO from Global Blood Therapeutics. GBT currently has a Phase III study underway with GBT440 for sickle cell anemia. Earlier he served as head, drug discovery at Incyte Pharmaceuticals. During his tenure at Incyte, the company was transformed from a genomics information company to one focused on drug discovery, culminating in the discovery of Jakafi, a JAK1/2 kinase inhibitor. | Show More
Jakafi was approved for the treatment of myelofibrosis by the FDA in 2011. Prior to Incyte, Metcalf was the chief scientific officer of Kosan Biosciences. Prior to that, he served in a number of executive management positions with SmithKline Beecham over the course of 17 years, most recently as worldwide head of discovery chemistry and platform technologies. Dr. Metcalf is credited with the discovery Sabril, for epilepsy and has numerous patents and publications in the drug discovery arena. | show less
Maria Trojanowska, PhD
Dr. Trojanowska is a Professor of Medicine and Director of the Arthritis Center at the Boston University School of Medicine. An expert in immunology and fibrotic diseases, her research focuses on the molecular and cellular mechanisms that underlie pathogenic processes responsible for tissue fibrosis and vasculopathy in scleroderma.
Suzanne Ostrand-Rosenberg, PhD
Dr. Ostrand-Rosenberg has more than 40 years of experience leading investigations focused on the immune system’s response to cancer. She is currently the Robert & Jane Meyerhoff Professor of Biochemistry, Emeritus, and Professor of Biological Sciences, Emeritus, University of Maryland Baltimore County, Baltimore, MD, and has been working with the University since 1977. She was also appointed as the Adjunct Professor of Pathology, Huntsman Cancer Institute (HCI), University of Utah, Salt Lake City, UT, in 2018. | Show MoreIn the 1980s and 1990s, Dr. Ostrand-Rosenberg and her team were instrumental in demonstrating the importance of CD4+ T-helper lymphocytes. Since 1990, her team has pioneered studies on myeloid-derived suppressor cells (MDSCs) in fighting cancer and has led the development of novel cell-based immuno-therapeutics. Additionally, Dr. Ostrand-Rosenberg’s research on the Programmed Death Ligand 1 pathway (PD-L1) resulted in the discovery of two novel anti-PD-L1 therapeutics. Dr. Ostrand-Rosenberg has served as an editor of multiple immunology and cancer journals, has regularly reviewed grants for national and international scientific organizations, and has served on the NCI Board of Scientific Counselors. One of her team’s publications was recognized as the most cited publication in the Journal of Immunology in 2021. She has been the recipient of numerous scientific awards, including Distinguished Lecturer, German Cancer Research Center (DKFZ), Heidelberg in 2012 and Distinguished Fellow of the American Association of Immunologists in 2020. She was appointed by Maryland’s governor to the State of Maryland Human Stem Cell Commission from 2007-2013. Dr. Ostrand-Rosenberg obtained her BA in Biology from Barnard College of Columbia University and her PhD in Immunology from California Institute of Technology and completed her postdoctoral studies in Immunology at Johns Hopkins University. | Show less
Charles Sidman, PhD, MBA
Dr. Sidman currently serves as Founder and Managing Partner, ECS Capital Partners, LLC. Dr. Sidman’s academic career includes experience as Research Fellow in Pathology at Harvard Medical School, Member of the Basel Institute for Immunology in Basel, Staff Scientist at The Jackson Laboratory in Bar Harbor, and Professor of Molecular Genetics, Biochemistry, Microbiology, and Management at the University of Cincinnati. His first professional effort was in computer science, in which he pioneered what became known decades later as Artificial Intelligence. In biomedicine, he worked with eminent colleagues in genetics and immunology to help enable current exciting applications in these fields. | Show More
Dr. Sidman has invested in multiple start- up companies through over 100 rounds, acted as Chairman of 4, and board member of another 5. He is Founding Chairman of Maine Angels, Founding Member of the Angel Capital Association, former Board Member of the World Business Angel Forum, former Chair of the Strategy and Education Committees of the National Association of Seed and Venture Funds, Founding Member and President of the Crowdfunding Professional Association, and recipient of special recognition from the European Business Angel Network. Dr. Sidman earned his AB degree in Biochemical Sciences, AM degree in Biochemistry, and PhD in Immunology, all from Harvard, and his MBA from the University of Cincinnati. He has lectured or consulted at some of the world’s leading universities, research centers and companies, and has authored over 100 publications in immunology, patent reform, crowdfunding, and government roles in tech transfer and early-stage investing. | show less